Intro to CBD

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The Endocannibinoid System

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How Terpenes Work Synergistically with Cannabinoids

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CBD Deep Science

Cannabinoids Working at the Cellular Level

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CBD Oil for Pets

Cannabinoids Working at the Cellular Level

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CBD Hemp Oil Basics

Cannabidiol (CBD) Hemp Oil regulates the ebb and flow of calcium and stress, autophagy and cell death, the restoration of homeostasis on a cellular level.

Over just the last two decades, more than 20,000 scientific studies and research projects have investigated the beneficial role of Cannabinoids in our systems. The endocannabinoid system and potential for health benefits and improved homeostasis (the process of stabilizing one’s health) obtained through natural CBD hemp oil supplements.

How Does Your Body Metabolize CBD?

The potential health benefits of cannabinoids as in CBD Hemp Oil are thanks in part to the way our body breaks them down through Metabolization. When you take CBD orally, it processes in much the same way as other oral drugs. Cannabidiol (CBD Hemp Oil) enters into the digestive tract and slowly absorbs through the stomach lining into the hepatic portal system. The hepatic portal system is actually a vital system of veins connecting the stomach to the liver, and also acts as one of the body’s filter systems.

What are Cannabinoids?

Cannabinoids are receptors throughout our brain and body and contained in what is called the System within (Endo) our body.

Cannabinoids promote neuroplasticity and mediate homeostasis through various bidirectional pathways. The actions of CBD a prime way that the endocannabinoid system regulates cellular repair and renewal. Cannabinoids enhance mitochondrial function and restore physiological balance.

CBD is a potent antioxidant, according to the U.S. government, which filed a patent on the antioxidant and neuroprotective properties of cannabinoids based on research from 1998.

The Endocannabinoid System (ECS)

We are hard-wired with a system of Cannabinoid receptors throughout our brain and body. When these receptors are activated they permit 2-way communication between body systems, something that the science books had previously taught was impossible.

The system called the Endocannabinoid System (ECS) literally means “the Cannabinoid system inside the body”. By regularly supplying our ECS with the nutrients it was designed for, vital communications can be restored between the control centers of the body and every other system.

Endocannabinoids are neurotransmitters that work in both the central & peripheral nervous systems by binding to cannabinoid receptors and receptor proteins. It is a homeostatic regulator found in mammals that helps to modulate all other systems in the body.
Currently, science has isolated two cannabinoids that originate from within the body CBD1 & CBD2. (for CBD detailed information click here)

Endocannabinoid described as a system because it’s an inter-connected series of mechanisms, (and called ‘ECS’ for short), it’s made of three primary components:

  1. Cells that allow the receipt and transmission of cannabinoid receptors.
  2. Specific enzymes tasked with creating or eliminating cannabinoids
  3. Endocannabinoids, which your body naturally produces and resemble cannabinoid compounds.

Together, they foster communication within the body, allowing your biological functions and responses to work optimally. Scientific studies confirm that the endocannabinoid system plays many vital roles throughout the body.

Endocannabinoid Deficiency (ECD) is having a lack of endocannabinoids and hence a state of Endocannabinoid Deficiency.

What happens when you have an endocannabinoid deficiency?

Scientists have given the label Clinical Endocannabinoid Deficiency Syndrome (CECD) to the state when our endocannabinoid system becomes compromised or weakened, as proper regulation and balance is disrupted.
When Clinical Endocannabinoid Deficiency (CECD) occurs, a person’s body doesn’t naturally produce enough cannabinoids. Therefore, this individual lack sufficient chemical messengers to regulate their systems, including controlling the duration and intensity of many of our physiological processes in the brain reproductive organs, nervous system, and more.

Why we should supplement with cannabinoids?

Scientists believe that with Clinical Endocannabinoid Deficiency (CECD), a person’s body doesn’t naturally produce enough cannabinoids. Therefore, this individual lack sufficient chemical messengers to regulate their systems, including controlling the duration and intensity of many of our physiological processes in the brain reproductive organs, nervous system, and more.

Active Ingredients Make Supplements Work

At SilverLeaf Global, we significantly minimize the use of inactive fillers and additives to achieve our committed goal to deliver the highest quality, purity, and integrity possible.

From the onset, SilverLeaf’s primary objective is to deliver the highest concentration of active ingredients possible. Fillers and additives provide no substantial value and are primarily used to achieve the appearance of getting more in volume per dollar spent.
We firmly stand on the belief that by minimizing the use of fillers allows our active blend to establish the best synergy between our blend of CBD and terpenes and the optimal delivery utilized by the body by preventing inactive filler interference.

The evidence is clear upon inspection of how we deliver our NANOSOL™ Pro product line of broad spectrum CBD hemp oil. All NANOSOL™ Pro CBD hemp oil product come in 0.50 FL oz./15 ml droppers were mathematically selected to deliver the highest concentration possible. Our CBD strength (shown in milligrams) contained in each bottle is formulated to verifiably deliver 90% or greater raw natural active ingredients. We use less than 10% of inactive ingredients (fillers), and those used are pharmaceutical grade (MCT coconut or similar) simply to top off the active ingredients.

Further to the point, the NANOSOL™ Pro dose recommendation found on our labels shows delivery of expected CBD milligrams in a small number of drops, while most others suggest a full dropper to achieve the same dose. If we used a 1 oz. / 30ml dropper bottle, it would require us to increase the filler we use by over 50%, which we believe diminishes the overall benefit of supplemental use.

Additives generally have little or no nutritional value. The objective of taking a dietary supplement is for the active ingredients to be best utilized by our bodies. The best nutritional supplements stimulate optimal uptake (bio-availability) and maximize the effectiveness of the supplemental nutrients consumed.

Understanding the above maximizes the dollars you spend in achieving the greatest effectiveness for your supplemental objectives.

Buyer Awareness

Nutritional/Dietary Supplement Facts

Nutritional/Dietary Supplement Regulation

Nutritional/dietary supplements are defined as a category of food and not a drug, both having different regulations. Unlike other products, the regulation for dietary supplements is that they are considered safe until proven unsafe.

Because of this unique regulation approach, the best way to achieve the optimal outcome when implementing CBD into a daily supplementation routine is for both the consumer and supplier to invest the time up front to verify the product.

Below are several guidelines and checklists that we hope help you make an informed decision.

CBD Hemp Oil Validation Process

Understand why you are taking a supplement

Assess Credibility

Avoid marketing hype and unsubstantiated claims. Just because it’s in print does not mean its fact. Let your education of supplier, product, and the scientific transparency available to you be your foundational guiding light.

Assess the Relevance

Once you verify the product claim is in good standing, take a few moments of your time to understand the product relevance to your goals.

Evaluate the Safety

Ensuring supplemental safety is primarily the responsibility of the supplier and the consumer. The easiest way to understand safety is by reading the product’s associated Certificate of Analysis report. It should be batch-specific and not a generic Certificate of Analysis.

Evaluate the Risks Vs. Benefits

Benefits are understood because they are headliners in marketing and used to encourage the purchase of a product. Risks may be called “counter indications” or “side effects,” but many times they are hidden or in small print in hopes they do not dissuade a customer from buying. We suggest reading the smaller print first, or, said differently, read from the bottom up to ensure you have a full understanding of benefits and risks.

Make an Informed Decision

After you have ensured product integrity and transparency, you are armed to make an informed decision. We put together a CBD Hemp Oil checklist that is intended to guide you in making a better decision on product and provider.

Try Our Helpful Hemp Buyer Checklist


More CBD Science

Further reading about CBD and the endocannibinoid system